Jan Wehkamp : rechercher sur Z-Library

Journal of Translational Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 126 KB

english, 2009

Antibacterial activity of human defensins on anaerobic intestinal bacterial species: a major role of HBD-3

Sabine Nuding, Lutz T. Zabel, Corinne Enders, Edith Porter, Klaus Fellermann, Jan Wehkamp, Holger A.G. Mueller, Eduard F. Stange

Journal:

Microbes and Infection

Année:

2009

Langue:

english

Fichier:

PDF, 516 KB

english, 2009

Breakdown of antimicrobial host defense barrier as trigger of chronic inflammatory bowel diseases

Jan Wehkamp

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 75 KB

english, 2011

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

Schroeder, Bjoern O., Wu, Zhihong, Nuding, Sabine, Groscurth, Sandra, Marcinowski, Moritz, Beisner, Julia, Buchner, Johannes, Schaller, Martin, Stange, Eduard F., Wehkamp, Jan

Journal:

Nature

Année:

2011

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2011

Inducible and constitutive β-defensins are differentially expressed in Crohn's disease and ulcerative colitis

Jan Wehkamp, Juergen Harder, Michael Weichenthal, Oliver Mueller, Klaus R. Herrlinger, Klaus Fellermann, Jens M. Schroeder, Dr. Eduard F. Stange

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 287 KB

english, 2003

Serum procalcitonin differentiates inflammatory bowel disease and self-limited colitis

Klaus R. Herrlinger, Rike Dittmann, Gunther Weitz, Jan Wehkamp, Diether Ludwig, Matthias Schwab, Eduard F. Stange, Klaus Fellermann

Journal:

JAN WEHKAMP, EDUARD F. STANGE

Année:

2004

Langue:

english

Fichier:

PDF, 91 KB

english, 2004

A New Look at Crohn's Disease : Breakdown of the Mucosal Antibacterial Defense

Journal:

Annals of the New York Academy of Sciences

Année:

2006

Langue:

english

Fichier:

PDF, 237 KB

english, 2006

Intestinal bacterial translocation in rats with cirrhosis is related to compromised paneth cell antimicrobial host defense

Zora Teltschik, Reiner Wiest, Julia Beisner, Sabine Nuding, Claudia Hofmann, Juergen Schoelmerich, Charles L. Bevins, Eduard F. Stange, Jan Wehkamp

Journal:

Hepatology

Année:

2012

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2012

Is there a role for defensins in IBD?

Jan Wehkamp, Eduard F. Stange

Journal:

Maureen J. Koslowski, Julia Beisner, Eduard F. Stange, Jan Wehkamp

Année:

2008

Langue:

english

Fichier:

PDF, 217 KB

english, 2008

In vivogene expression profiling of human intestinal epithelial cells: analysis by laser microdissection of formalin fixed tissues

Michael D George, Jan Wehkamp, Robert J Kays, Christian M Leutenegger, Sadiah Sabir, Irina Grishina, Satya Dandekar, Charles L Bevins

Journal:

BMC Genomics

Année:

2008

Langue:

english

Fichier:

PDF, 801 KB

english, 2008

Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis

Michael Gersemann, Svetlana Becker, Irmgard Kübler, Maureen Koslowski, Guoxing Wang, Klaus Robert Herrlinger, Joscha Griger, Peter Fritz, Klaus Fellermann, Matthias Schwab, Jan Wehkamp, Eduard Friedri

Journal:

Differentiation

Année:

2009

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2009

Paneth cell antimicrobial peptides: Topographical distribution and quantification in human gastrointestinal tissues

Jan Wehkamp, Hiutung Chu, Bo Shen, Ryan W. Feathers, Robert J. Kays, Sarah K. Lee, Charles L. Bevins

Journal:

FEBS Letters

Année:

2006

Langue:

english

Fichier:

PDF, 524 KB

english, 2006

Innate antimicrobial host defense in small intestinal Crohn's disease

Journal:

International Journal of Medical Microbiology

Année:

2010

Langue:

english

Fichier:

PDF, 877 KB

english, 2010

A flow cytometric assay to monitor antimicrobial activity of defensins and cationic tissue extracts

Sabine Nuding, Klaus Fellermann, Jan Wehkamp, Holger A.G. Mueller, Eduard F. Stange

Journal:

Journal of Microbiological Methods

Année:

2006

Langue:

english

Fichier:

PDF, 307 KB

english, 2006

NOD2 mutation and mice: no Crohn's disease but many lessons to learn

Jan Wehkamp, Eduard F. Stange

Journal:

Trends in Molecular Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 88 KB

english, 2005

A Chromosome 8 Gene-Cluster Polymorphism with Low Human Beta-Defensin 2 Gene Copy Number Predisposes to Crohn Disease of the Colon

Klaus Fellermann, Daniel E. Stange, Elke Schaeffeler, Hartmut Schmalzl, Jan Wehkamp, Charles L. Bevins, Walter Reinisch, Alexander Teml, Matthias Schwab, Peter Lichter, Bernhard Radlwimmer, Eduard F.

Journal:

The American Journal of Human Genetics

Année:

2006

Langue:

english

Fichier:

PDF, 420 KB

english, 2006

More than a marine propeller – the flagellum of the probiotic Escherichia coli strain Nissle 1917 is the major adhesin mediating binding to human mucus

Anja Troge, Wolfgang Scheppach, Bjoern O. Schroeder, Stefan A. Rund, Klaus Heuner, Jan Wehkamp, Eduard F. Stange, Tobias A. Oelschlaeger

Journal:

International Journal of Medical Microbiology

Année:

2012

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2012

Construction of recombinant E. coli Nissle 1917 (EcN) strains for the expression and secretion of defensins

Ean-jeong Seo, Stephanie Weibel, Jan Wehkamp, Tobias A. Oelschlaeger

Journal:

International Journal of Medical Microbiology

Année:

2012

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2012

Paneth's disease

Jan Wehkamp, Eduard F. Stange

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 472 KB

english, 2010

Results of the 2nd Scientific Workshop of the ECCO (III): Basic mechanisms of intestinal healing

Florian Rieder, Thomas Karrasch, Shomron Ben-Horin, Anja Schirbel, Robert Ehehalt, Jan Wehkamp, Colin de Haar, Dominique Velin, Giovanni Latella, Franco Scaldaferri, Gerhard Rogler, Peter Higgins, Miq

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 391 KB

english, 2012

Olfactomedin-4 is a glycoprotein secreted into mucus in active IBD

Michael Gersemann, Svetlana Becker, Sabine Nuding, Lena Antoni, German Ott, Peter Fritz, Naohide Oue, Wataru Yasui, Jan Wehkamp, Eduard F. Stange

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2012

130 Activated Innate Immune System in Irritable Bowel Syndrome?

Jost Langhorst, Angela Junge, Andreas Rueffer, Jan Wehkamp, Dirk Foell, Andreas Michalsen, Frauke Musial, Gustav J. Dobos

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 69 KB

english, 2008

535 Auto-Regulation of Human Tcf-4 By Wnt-β-Catenin-Tcf-4 Signaling

Guoxing Wang, Oliver Burk, Eduard Stange, Jan Wehkamp

Journal:

Jan Wehkamp, Juergen Harder, Birte von Meissner, Klaus Robert Herrlinger, Eduard Friedrich Stange, Klaus Fellermann, Jens Michael Schroeder

Année:

2008

Langue:

english

Fichier:

PDF, 116 KB

english, 2008

Human β-defessin 3: A novel antimicrobial peptide preferentially expressed in ulcerative celitis

Journal:

Wang, Guoxing, Stange, Eduard F, Wehkamp, Jan

Année:

2001

Langue:

english

Fichier:

PDF, 185 KB

english, 2001

Host–microbe interaction: mechanisms of defensin deficiency in Crohn’s disease

Journal:

Expert Review of Anti-infective Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 214 KB

english, 2007

S1757 Tcf-1 Mediated Wnt Signaling Influences Intestinal Innate Immune Defense in Crohn's Disease

Beisner, Julia, Koslowski, Maureen J., Stange, Eduard, Wehkamp, Jan

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 50 KB

english, 2010

Tu1760 Functional Evidence for a Causative Role of the Intestinal Microbiota in Crohn's Disease-Like Ileitis Using Antibiotic-Treated and Germ-Free TNFDeltaare/+ Mice

Schaubeck, Monika, Clavel, Thomas, Waldschmitt, Nadine, Wehkamp, Jan, Martinez, Ines, Walter, Jens, Kollias, George, Haller, Dirk

Journal:

Troge, Anja, Wehkamp, Jan, Oelschlaeger, Tobias A.

Année:

2014

Langue:

english

Fichier:

PDF, 146 KB

english, 2014

Tu1971 Probiotic Escherichia coli Strain Nissle 1917 Binds to Gluconat of Mucin2/ Human Mucus via Its Flagellum

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 137 KB

english, 2013

T1251 Antimicrobial Host Defense in the Upper Gastrointestinal Tract

Hosaka, Yoshio, Koslowski, Maureen J., Nuding, Sabine, Wang, Guoxing, Schlee, Miriam, Schäfer, Christian, Saigenji, Katunori, Stange, Eduard, Wehkamp, Jan

Journal:

Herrlinger, Klaus R., Barthel, Daniel N., Schmidt, Klaus J., Barthel, Christiane S., Büning, Jürgen, Wehkamp, Jan, Stange, Eduard, Fellermann, Klaus

Année:

2008

Langue:

english

Fichier:

PDF, 70 KB

english, 2008

T1022 Infliximab as Rescue Medication for Patients With Severe Ulcerative/Indeterminate Colitis Refractory to Tacrolimus and Vice Versa

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 44 KB

english, 2010

M1200 Probiotic E. coli (Symbioflor®2) Treatment Mediates Antimicrobial β-Defensin (HBD-2) Synthesis and Fecal Excretion in Humans

Schlee, Miriam, Zimmermann, Kurt, Huber, Hermann, Fellermann, Klaus, Stange, Eduard, Wehkamp, Jan

Journal:

Becker, Svetlana, Beisner, Julia, Gersemann, Michael, Koslowski, Maureen J., Wehkamp, Jan, Stange, Eduard

Année:

2008

Langue:

english

Fichier:

PDF, 85 KB

english, 2008

S1766 Regulation of Goblet Cell Differentiation Factors HATH1 and KLF4 in Intestinal Epithelial Cells

Journal:

Wehkamp, Jan, Fellennann, Klaus, Herrlinger, Klaus Robert, Baxmann, Steffi, Schmidt, Klaus, Rudolph, Burkhard

Année:

2010

Langue:

english

Fichier:

PDF, 53 KB

english, 2010

Human beta defensin 2 is induced in ulcerative colitis but not in Crohn's disease

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 193 KB

english, 2000

Human colonic mucus is a reservoir for antimicrobial peptides

Antoni, Lena, Nuding, Sabine, Weller, Dagmar, Gersemann, Michael, Ott, German, Wehkamp, Jan, Stange, Eduard F.

Journal:

Koslowski, Maureen J., Wang, Guoxing, Kuebler, Irmgard E., Gersemann, Michael, Fellermann, Klaus, Stange, Eduard, Wehkamp, Jan

Année:

2013

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2013

T1242 Selective Influence of Tcf-4 Mediated Wnt Signaling On Intestinal Innate and Adaptive Immunity of Ileal Crohn's Disease

Journal:

Schmidt, Klaus, Fellermann, Klaus, Wehkamp, Jan, Herrlinger, Klaus Robert, Reimann, Frank Martin, Baxmann, Steffi, Stange, Eduard Friedrich

Année:

2008

Langue:

english

Fichier:

PDF, 70 KB

english, 2008

Distribution of defensin expression in the upper gastrointestinal tract

Journal:

Ostaff, Maureen J., Stange, Eduard Friedrich, Wehkamp, Jan

Année:

2000

Langue:

english

Fichier:

PDF, 176 KB

english, 2000

Antimicrobial peptides and gut microbiota in homeostasis and pathology

Journal:

EMBO Molecular Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 965 KB

english, 2013

Mechanisms of Disease: defensins in gastrointestinal diseases

Wehkamp, Jan, Fellermann, Klaus, Herrlinger, Klaus R, Bevins, Charles L, Stange, Eduard F

Journal:

Nature Clinical Practice Gastroenterology & Hepatology

Année:

2005

Langue:

english

Fichier:

PDF, 699 KB

english, 2005

Elevated Human β-Defensin-2 Levels Indicate an Activation of the Innate Immune System in Patients With Irritable Bowel Syndrome

Langhorst, Jost, Junge, Angela, Rueffer, Andreas, Wehkamp, Jan, Foell, Dirk, Michalsen, Andreas, Musial, Frauke, Dobos, Gustav J

Journal:

American Journal of Gastroenterology

Année:

2009

Langue:

english

Fichier:

PDF, 172 KB

english, 2009

Defective Paneth Cell—Mediated Host Defense in Pediatric Ileal Crohn's Disease

Perminow, Gøri, Beisner, Julia, Koslowski, Maureen, Lyckander, Lars Gustav, Stange, Eduard, Vatn, Morten H, Wehkamp, Jan

Journal:

American Journal of Gastroenterology

Année:

2010

Langue:

english

Fichier:

PDF, 257 KB

english, 2010

NOD2/CARD15 Gene Variants Are Linked to Failure of Antibiotic Treatment in Perianal Fistulating Crohn's Disease

Angelberger, Sieglinde, Reinisch, Walter, Dejaco, Clemens, Miehsler, Wolfgang, Waldhoer, Thomas, Wehkamp, Jan, Lichtenberger, Cornelia, Schaeffeler, Elke, Vogelsang, Harald, Schwab, Matthias, Teml, Al

Journal:

American Journal of Gastroenterology

Année:

2008

Langue:

english

Fichier:

PDF, 201 KB

english, 2008

Tu1835 Inflammatory Cells Enhance Defensin Expression via Peripheral Wnt Factors, Which Is Impaired in Ileal CD Patients

Courth, Lioba F., Ostaff, Maureen J., Stange, Eduard F., Wehkamp, Jan

Journal:

Ostaff, Maureen J., Schäfer, Christian, Courth, Lioba F., Stebe, Sabrina R., Ott, German, Stange, Eduard F., Wehkamp, Jan

Année:

2015

Langue:

english

Fichier:

PDF, 66 KB

english, 2015

Sa1728 Chronic Alcohol Abuse Induces Paneth Cell Antimicrobial Expression in Gastric Mucosa - A Consequence of Wnt Signaling Aberrations?

Journal: